Understanding the mechanisms of evasive resistance in cancer is of great importance to develop efficient therapies. Analyzing the molecular mechanisms underlying therapy resistance of hepatocellular carcinoma (HCC). we have discovered a kinase-activity independent role of LATS1 (large tumor suppressor) but not LATS2 in regulating sorafenib-induced lethal autophagy in HCC. We have foun... https://www.jmannino.com/quick-buy-Ellakai-Shorts-Cutwork-limited-choice/
LATS1-Beclin1 mediates a non-canonical connection between the Hippo pathway and autophagy
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